article RTB AFH 10 Jan 2023

 


Congratulations to the China Children's Cancer Group Acute Lymphoblastic Leukemia (CCCG-ALL) Study Group on its significant global contributions in paediatric oncology.


VIVA Foundation for Children with Cancer (VIVA-Singapore) in Singapore’s partnership and collaboration with VIVA China Children’s Cancer Foundation (VIVA-China) has resulted in tremendous success in the CCCG-ALL Study Group. The CCCG-ALL Study Group has now enrolled over 16,000 children across 26 hospitals in China and Hong Kong SAR and published 23 articles on the findings from the study group’s research. In addition, Dr Cai, Director of VIVA China, established a Survivorship Programme at National Children’s Medical Center and Shanghai Children’s Medical Center, which has produced three high-quality publications, including one expert consensus. The collaborative study culminated in a notably high five-year survival rate of 91% for ALL.  


VIVA-Singapore is excited that our partnership with VIVA-China has profound impact in advancing paediatric ALL research and survivorship care in China and beyond -- for the children with cancer.


We also thank Dr Pui Ching-Hon, our Chair of External Advisory Board (VIVA-Singapore), for his continuous and invaluable support in this collaboration to advance paediatric ALL research and survivorship care in China, Singapore and the region.

 

CCCG-ALL Study Group Publications

 

Title

Journal

Year

1

Treatment abandonment in childhood acute lymphoblastic leukemia in China: a retrospective cohort study of the Chinese Children’s Cancer Group.

Archives of Disease in Childhood.

2019

2

Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia chromosome-positive Acute Lymphoblastic Leukemia: A Randomized, Open-label, Multicenter study of the Chinese Children’s Cancer Group.

JAMA Oncology.

2020

3

Septicemia after chemotherapy for childhood acute lymphoblastic leukemia in China: A multicenter study CCCG-ALL-2015.

Cancer Med.

2020

4

Pulse therapy with vincristine and dexamethasone in childhood acute lymphoblastic leukemia: a multicenter, open-label, randomized, phase 3 non-inferiority study.

Lancet Oncol.

2021

5

Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiation.

Blood.

2021

6

Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemia.

Scientifc Reports

2021

7

The International Collaboration to Save Children With Cancer

JAMA Oncology.

2021

8

Reduced Dose Intensity of Daunorubicin During Remission Induction for Low-Risk Patients With Acute Lymphoblastic Leukemia: A Retrospective Cohort Study of the Chinese Children’s Cancer Group.

Front Oncol.

2022

9

Extended vincristine and dexamethasone pulse therapy may not be necessary for children with TCF3‐PBX1 positive acute lymphoblastic leukaemia.

British Journal of Haematology

2022

10 

A prospective Multicenter Study on Varicella-Zoster Virus Infection in Children with acute lymphoblastic leukemia.

Front Cell Infect Microbiol.

2022

11 

Prognostic significance of steroid response in pediatric acute lymphoblastic leukemia: The CCCG-ALL-2015 Study

Front Oncol

2022

12 

Report of Chinese Children′s Cancer Group acute lymphoblastic leukemia 2015 multicenter study

Chin J Pediatr

2022

13

Prognostic factors of childhood acute lymphoblastic leukemia with TCF3-PBX1 in CCCG-ALL-2015: a multi-center study

Cancer

2023

14

Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese Children’s Cancer Group-ALL-2015

Frontiers of Mdicine

2023

15

Effect of the tyrosine kinase inhibitors on the growth in children with Philadelphia chromosome–positive acute lymphoblastic leukemia: a case–control study

Lancet Regional Health – Western Pacific

2023

16

Causes of death and treatment-related mortality in newly diagnosed childhood acute lymphoblastic leukemia treatment with Chinese Children's Cancer Group study ALL-2015

Annals of Hematology

2023

17

Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China

Leukemia

2023

18

Outcome of infants with acute lymphoblastic leukemia treated with the Chinese Children’s Cancer Group Acute Lymphoblastic Leukemia 2015 study protocol

Haematologica

2024

19

COVID-19 infection in children with acute lymphoblastic leukemia in China: Mild clinical course after Omicron infection

Chinese Medical Journal

2024

20

Delineation of features, responses, outcomes, and prognostic factors in pediatric PDGFRB‐positive acute lymphoblastic leukemia patients: A retrospective multicenter study

Cancer

2024

21

Prognostic and therapeutic implication of measurable residual disease levels during remission induction of childhood ALL

Blood.

2025

22

Risk factors and outcomes of asparaginase-associated pancreatitis in pediatric ALL patients

Blood.

2025

23

A Multicenter Study of Acute Abdomen in Children With Acute Lymphoblastic Leukemia: CCCG‐ALL‐2015

Cancer Medicine

2025