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Updates on HSCT for Childhood Leukaemia

Saturday, 22 Aug 2020
15:00-17:00 (UTC+8)



The most common diseases treated with allogeneic hematopoietic stem cell transplantation in children are acute leukemias. With recent advances in transplant regimens and supportive care, the outcome of patients has steadily improved. Many controversies in pre- and post-transplant care remain, and the optimal approaches have yet been determined. In this webinar, Prof Leung will go over several controversial issues and outline some conceptual frameworks in transplant in a question-and-answer format.

The main presentation by Prof Wing Leung (KKH) will be followed by interactive case discussions with expert panel comprising Prof Wing Leung, Dr Pamela Lee (HKU), Assoc Prof Tan Poh Lin (NUH), moderated by Prof Hany Arifin (UMMC)

Submission of cases for discussion will only be open to VABMT Consortium members. This webinar is only for healthcare professionals.


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Prof Leung Wing Hang

Senior Consultant, Haematology/Oncology Service Director
Senior Consultant, Paediatric Bone Marrow Transplant and Cell Therapy Centre
KK Women's and Children's Hospital
Member, VIVA External Advisory Board

Professor Leung is Chair of TCL-CCF Distinguished Professorship in Paediatric Oncology and Professor at Duke-NUS Medical School. He is Senior Consultant in Hematology and Oncology and Director of Paediatric Bone Marrow Transplant and Cell Therapy Centre at KK Women’s and Children’s Hospital. He is Director of Research at SingHealth Duke-NUS Transplant Centre.

Previously, he was a faculty member at Johns Hopkins University and St. Jude Children’s Research Hospital and Vice President of Clinical Development at Miltenyi Biotec. Prof. Leung obtained his medical degree from the University of Hong Kong and Ph.D. from the Johns Hopkins University. He is a diplomate certified in general pediatrics and in pediatric hematology-oncology by the American Board of Pediatrics. Prof. Leung has a major research interest in the biology of human natural killer cells and memory T cells, specifically the clinical applications in HLA-mismatched transplantation and immune effector cell therapy. His research received continuous funding from the National Institutes of Health. He served as a member in the NCI Study Section, NHLBI BMT-CTN Protocol Review Committee, and Journal of Clinical Oncology Editorial Board. He is an elected member of the American Society for Clinical Investigation.


Assoc Prof Tan Poh Lin

Senior Consultant and Clinical Director of Paediatric Blood / Marrow Transplantation (BMT) Programme, Department of Paediatrics 
Khoo Teck Puat - National University Children's Medical Institute
National University Health System (NUHS), Singapore

Dr. Tan is a clinician-educator experienced in the field of paediatric haematopoietic cell transplant (HCT). She has more than 20 years of clinical experience in HCT and more than 10 years of experience mentoring regional clinical doctors in HCT. As the field of HCT expands to include immune effector cells therapy, Dr. Tan and her team have been studying how best to implement therapeutics to achieve quality of life with cure.  


Dr Pamela Lee

Clinical Associate Professor Department of Paediatrics and Adolescent Medicine
LKS Faculty of Medicine, The University of Hong Kong 
Honorary Consultant, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital; Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital
Department of Pediatrics, HKU-Shenzhen Hospital

Dr Pamela Lee is specialized in clinical immunology and haematopoietic stem cell transplantation. She received training in the Great Ormond Street Hospital for Children, London and is currently appointed as Honorary Consultant for the HSCT service at the Hong Kong Children’s Hospital and The HKU-Shenzhen Hospital. Pamela is a lead organizer for a series of ‘Summer Schools’ for the Asia Pacific Society for Primary Immunodeficiencies (APSID) and The Viva-Asia Blood and Marrow Transplant (VABMT) Consortium since 2015 and 2017, respectively. These educational events are conducted in learner-centered, interactive manners targeted to trainees’ learning needs. She aspires to promote the concept of ‘Train the Trainers’ amongst young doctors, who should equip themselves with teaching and supervisory capabilities as part of their professional development.​ 


Prof Hany Ariffin

Head and Senior Consultant Paediatric Haematology-Oncology and Blood & Marrow Transplantation Unit
University of Malaya Medical Centre
Kuala Lumpur, Malaysia

Professor Hany Ariffin is Professor of Paediatrics and Head of the Division of Paediatric Haematology-Oncology and Bone Marrow Transplantation at the University of Malaya Medical Centre (UMMC). She also heads the Biobank Unit in the Faculty of Medicine, UM.  Her main research interest is childhood leukaemia and she has been the Malaysian lead for the Malaysia-Singapore (MASPORE) Leukaemia Study Group since 2003. Her other research areas include childhood cancer survivorship, stem cell transplantation and inherited cancers, particularly related to mutations in the tumour suppressor gene, TP53In 2015, she won the Anugerah Akademik Negara award and in 2018 received the Distinguished Researcher Award from University Malaya.

Professor Hany is a member of the paediatric oncology accreditation committee for the National Specialist Register,  co-chair of the Viva-Asia Bone Marrow Transplantation Consortium and a past president of the Malaysian Society of Paediatric Haematology-Oncology. Together with colleagues in the local fraternity, Professor Hany works to improve the outcome of children with cancer in Malaysia whilst ensuring equitable treatment for all irrespective of socio-economic standing.