RTB 8 August 2022


VIVA-Asia Rare Tumour Board Webinar


Teratoma with Sarcomatous Transformation

Monday, 8 August 2022 |  5.30PM - 6.45PM (UTC+8 | SGT)  |  Check your Time Zone


VIVA-ASIA RARE TUMOUR BOARD WEBINAR is a virtual quarterly meeting that is organized by VIVA Foundation for Children with Cancer to enable doctors from all over the world to discuss the diagnosis and treatment of rare pediatric tumours.


Join us for a discussion on Teratoma with Sarcomatous Transformation. A team from KK Women and Children's Hospital from Singapore would be presenting a case on a patient who presented with anterior mediastinal mixed germ cell tumour. Dr Calvin Hoo and Dr Wai-fu Ng would be sharing the challenges of treatment while Dr Herbert Ho-fung Loong, Department of Clinical Oncology Deputy Medical Director, will enlighten us on the Implications of Somatic Transformation in Germ Cell Tumours. 

If you can't make it, you can still register to receive a copy of the webinar recording.

Medical professionals in Singapore may eligible for CME/CPE/CNE credits for attending this webinar.
Credits and Certificates of Attendance will only be issued for those who are able to attend the live session and are in adherence with VIVA's Attendance Policy.


  RTB Timetable



Title: Mediastinal germ cell tumour with early sarcomatous transformation by KKH

A review of the clinical course and the histopathology of a 14-year-old boy with a mediastinal mixed germ cell tumour with significant mass effect. He was treated with CCLG extracranial germ cell tumour protocol with normalisation of tumour markers. Prior to planned surgical resection, he was found to have multiple bony metastasis which was biopsied and found to be positive for poorly differentiated carcinoma. Resection of anterior mediastinal mass found components of immature teratoma, yolk sac tumour and high grade angiosarcoma.

Title: Teratoma with Malignant Transformation by HKCH

Teratoma with Malignant Transformation (TMT) is a rare disease entity. Hong Kong team would be presenting on how they manage these two cases of TMT. 

Title: Implications of Somatic Transformation on Germ Cell Tumours by Dr Loong, Herbert

Germ cell tumours with malignant somatic transformation represent an uncommon variant of what is typically a curable malignancy. There is a paucity of data on time of somatic transformation, response to conventional therapy, and survival outcomes of different somatic subtypes. In this talk, we aim to highlight current available evidence on this condition and discuss what may possibly be the most optimal approach in managing these patients.







Dr Herbert Loong

Dr Loong, Herbert Ho-fung

MBBS(HK), PDipMDPath(HK), MRCP(UK), FHKCP, FHKAM(Medicine) Associate Professor (Clinical) – Department of Clinical Oncology Deputy Medical Director – Phase 1 Clinical Trials Centre The Chinese University of Hong Kong, Hong Kong

Dr. Herbert Loong obtained his medical degree with a Distinction in Surgery from The University of Hong Kong in 2003. He subsequently completed his postgraduate internal medicine and medical oncology training in Queen Elizabeth Hospital and Prince of Wales Hospital in Hong Kong. He was admitted as a Member of the Royal College of Physicians (United Kingdom) in 2006 and a Fellow of the Hong Kong College of Physicians and Hong Kong Academy of Medicine in 2010.He has completed a Fellowship in Drug Development at Princess Margaret Cancer Centre in Toronto, Canada with special focuses on Experimental Therapeutics, Sarcoma Medical Oncology and Neuro-oncology. Dr. Loong joined The Chinese University of Hong Kong (CUHK) in March 2014 and is currently an Assistant Professor in the Department of Clinical Oncology, CUHK and the Deputy Medical Director of the Phase 1 Clinical Trials Centre, CUHK. He is also the Convenor of the Adult Sarcoma Multi-Disciplinary Tumour Board at Prince of Wales Hospital.His academic accolades include being the recipient of the Hong Kong Society for Neuro-oncology Traveling Scholarship in 2015 & 2016, an American Society of Clinical Oncology (ASCO) Merit Award in 2014, European Cancer Congress Fellowship Grant in 2013, European Society for Medical Oncology (ESMO) Preceptorship Award in 2012 & 2013, as well as an ESMO Translational Research Unit Visit Scholarship in 2012.



Calvin Hoo

Dr Hoo, Calvin

Resident Specialist
Department of Haematology and Oncology
Hong Kong Children's Hospital, Hong Kong

Amanda Kan

Dr Amanda Kan

Consultant, Department of Pathology
Hong Kong Children’s Hospital, Hong Kong


Dr Wai-Fu Ng

Dr Ng, Wai-fu

Consultant Pathologist
Hong Kong Children's Hospital, Hong Kong

Dr Amos Loh

Dr Loh, Amos

Senior Consultant, Department of Paediatric Surgery
Deputy Division Chair, Division of Surgery
Assistant Professor, Duke NUS Medical School
KK Women’s and Children’s Hospital, Singapore

Dr Soh Shui Yen

Dr Soh, Shui Yen

Head & Senior Consultant Haematology/Oncology Service
Paediatric Brain and Solid Tumour Programme
KK Women's and Children's Hospital, Singapore

Dr Lee York Tien

Dr Lee, York Tien

Department of Paediatric Surgery
KK Women’s and Children’s Hospital, Singapore

Dr Khurshid Merchant

Dr Merchant, Khurshid

Consultant Pathologist
Department of Pathology and Laboratory Medicine
KK Women’s and Children’s Hospital, Singapore

De Debbra Chong

Dr Chong, Debbra

Consultant, Haematology-Oncology Service
KK Women's and Children's Hospital, Singapore




Dr Anthony Liu

Dr Liu, Anthony

MBBS, MMedSc, FHKAM (Paed)
Clinical Assistant Professor
Department of Paediatrics & Adolescent Medicine
Hong Kong Children’s Hospital
LKS Faculty of Medicine, The University of Hong Kong

Prof Godfrey

Prof Chan, Godfrey 

Tsao Yen-Chow Endowed Professor in Paediatrics, HKU
Chief of Service, Department of Paediatrics,
Hong Kong Children’s Hospital and HKU-Shenzhen Hospital